For the problem of two-dimensional blanking of rectangular part, a sequential value correction blanking algorithm was proposed. Then, four-block nesting algorithm was constructed, and four-block nesting mode with upper bound on the number of rectangular parts was generated. Based on this pattern, the plate was divided into four blocks with each block contained strips of the same direction and each strip contained identical rectangular parts. Therefore, the four-block nesting algorithm was applied by the sequential heuristic algorithm to generate the nesting one by one. Under the condition of avoiding redundant rectangular parts，the maximum using times of each nesting mode were determined, and the value of rectangle in this nesting method was corrected after each nesting method was generated. Furthermore, the above sequential heuristic algorithm was iteratively executed multiple times to generate multiple blanking schemes, and the one with the least number of blanks was chosen as the final solution. Compared with the literature example, the results of numerical experiments show that the above algorithm saves blanks more than the literature algorithms.