In order to solve the cracking and springback defects of left and right side rails for the front floor of a certain vehicle model and improve the efficiency and reduce the number of die modifications, the stamping process of the entire process was simulated by finite element software Autoform. Then, taking the maximum thinning rate and maximum springback amount as evaluation indicators, the blanking holding force, die clearance, stamping speed and friction coefficient were optimized, and the reasonable value ranges of process parameters were obtained by the single factor control variable method. Furthermore, the optimal process parameters combination was obtained as the blanking holding force of 1000 kN, the die clearance of 1.5 mm, the stamping speed of 100 mm·s-1, and the friction coefficient of 0.13 by the orthogonal experiment, and among them, the stamping speed has the least impact on the target. The simulation results after process parameter optimization and iterative compensation of die surface show that the maximum thinning rate is decreased to 20.6%, eliminating the risk of cracking, and the maximum springback amounts of left and right side rails are 0.534 mm and 0.867 mm,respectively. The die verification shows that the parts have no cracking and the springback amount basically meets the size deviation of ±1.0 mm. Thus, through process parameter optimization and partial iterative compensation of  die surface, the risk of part cracking is avoided, the dimensional accuracy of part is improved, and the number of die modifications is reduced.