The finite element simulation and experimental research of aluminum alloy stamping forming of automotive body were carried out. The results show that the overall distribution of aluminum alloy sheet is uniform and the thinning rate is small, then the stamping force distribution, degree of thinning and thick anisotropy of aluminum alloy during the stamping forming process can be accurately analyzed. The formability of aluminum alloy sheet is hardly influenced by smaller thick anisotropy coefficient, thickness of aluminum alloy sheet is both thinner and thicker along the rolling direction, which at formed position changes greatly. The thickness variations of aluminum alloy sheet whose angle with rolling direction is 0 °, 45 ° and 90 ° are 0.27, 0.27 and 0.26 mm. The thickness variations of aluminum alloy sheet along different directions are also different, and the width variation of aluminum alloy sheet is 2.8 mm, whose rate of change is 0.2%. With the increasing of punch stroke, the stamping force is increasing gradually, then remains unchang, and also the stamping force tends to be smaller in the final stages of punch stroke, the maximum value of whose is about 80 kN.