For the auto girder, the influence of friction coefficient on the hot stamping for ultra high strength steel steel was analyzed by FEM simulation, and the influence of different lubrication conditions on the hot stamping for ultra high strength steel sheet was conducted by the hot stamping experiments. The results show that with the increasing of friction coefficient, the thickness of hot stamping parts becomes thinner, and the effective strain value becomes bigger. The hot stamping parts without lubricant have scratches, cracks and serious oxidation, and the hot stamping parts with graphite lubricant have scratches and cracks. However, the forming quality of hot stamping parts with glass lubricant is better, and the thickness of hot stamping parts increases gradually under three kinds of lubricant conditions. Thus, the glass lubricant is beneficial to the improvement of friction condition and oxidation resistance in the hot stamping process. Furthermore, the lubricant condition has little influence on the microstructure and mechanical properties of hot stamping parts, and the tensile strength of hot stamping parts is up to 1460 MPa and the microhardness is above 460 HV.