In order to speed up the production speed and save the cost of labor, material and time, for a kind of automotive transmission spline shaft, the process was changed to multi-station forging, and the synchronous research was conducted with the help of Deform-3D. Then, according to the shape characteristics of parts and the limit deformation degree of processed material, two theoretically reliable multi-station automatic forging processes were designed preliminarily, and the forming simulation of the two processes was completed by building a virtual forging experiment platform that met the actual conditions. Furthermore, according to the forming results, the process was evaluated, and the experimental results of equivalent stress and load change law were analyzed and compared. The results show that the two multi-station forging processes are basically feasible, and the process 1 performs better in the forming quality of part and the mold life. Finally, the manufacturing of transmission spline shaft is completed by reference to the process results through industrial experiments. The forging speed is fast, the production is stable, and the quality of part is good without cracks and other defects, which verifies the effectiveness of the multi-station forging process method.