Abstract: The microstructure, texture and mechanical properties of 6016 aluminum alloy sheets with different intermediate annealing processes were systematically studied by OM, SEM, TEM, XRD analysis and testing methods. The results show that with the extension of intermediate annealing time and the increase of annealing temperature, the grain size of 6016 aluminum alloy sheet in the intermediate annealing and finished states increases, AlFeSi phase in the matrix is not significant, while Mg2Si phases grow and coarsen to a certain extent, and the dislocations in the matrix are dissipated. The rolling texture and recrystallization texture are existence in 6016 aluminum alloy sheet after intermediate annealing treatment, but the proportion of texture in the substrate of sheet varies under different annealing processes. The finished sheet is mainly distributed with recrystallization textures such as Cube and CubeND, and the increase of recrystallization texture is beneficial for reducing the anisotropy of the alloy. The tensile strength, yield strength, and elongation are not significantly different under different intermediate annealing processes, and the formability of sheet is significantly affected by the intermediate annealing temperature.