A study on fatigue characteristics was conducted for the transformation induced plasticity steel HC380/590 TR. Then, the microstructure and mechanical properties of the transformation induced plasticity steel HC380/590TR and the traditional dual-phase steel HC340/590DP at the same strength grade were comparatively analyzed, and the tension-compression fatigue life test was carried out to obtain the fatigue life curve and the corresponding stress limit at the stress ratio of 0.1. Furthermore, based on the experimental test and Gerber formula, the fatigue life curve and the corresponding stress limit at the stress ratio of -1 were obtained, and the surface morphology and fracture morphology of the fatigue specimens were observed to analyze the crack source. The results show that the matrix structure of HC380/590TR steel consists of ferrite, bainite and martensite, and contains a certain amount of retained austenite. Compared with HC340/590DP steel at the same strength grade, the yield ratio of HC380/590TR steel increases by about 22.98%, the elongation after fracture increases by 49.04 %, and the work hardening index increases by 36.67%. And the fatigue ratio of HC380/590TR steel is about 0.4, which is slightly higher than that of HC340/590DP steel at the same strength grade. The fatigue cracks of HC380/590TR steel mainly initiate at the surface of specimen, and the initiation and propagation of cracks are relatively difficult, thus, its fatigue life is slightly higher than that of HC340/590DP steel.