The influences of two different diameters of rivets and four different dies on the mechanical response of self-piercing riveting joints   combining advanced high-strength steel HC340/590DP and cast aluminum material JDA1b were studied. The results show that the comparied to the group B joints with Φ5.5 mm rivet，the undercut value and shear peak force of the group A joints with Φ5.3 mm rivet are higher than that of group B joints. However, due to rivet fracture, its energy absorption value is lower than that of group B. The undercut values of A2 and B2 joints with the D-type dies are higher than that of the other joints, and the average shear peak force of A2 and B2 joints in the static tensile test is 6.76 kN, with the highest energy absorption values, showing better mechanical properties and stability. Compared with the die with a depth of 1.2 mm, the undercut value and bottom thickness of the joint   using the die with a depth of 1.0 mm are both increased. The failure mode of A2 and B2 joints using D-type dies is that the rivet is detached from the lower sheet, and the failure mode of the joints using E and F-type dies is a mixture of the rivet falling off the lower sheet and rivet fracture, and the rivet fracture is brittle fracture.